As a youthful kid, Lyonne was marked by the Ford Modeling Agency.

At six years old, she was given a role as Opal on Pee-small's Playhouse, trailed by film appearances in Heartburn, A Man Called Sarge, and Dennis the Menace. On functioning as an exceptionally youthful tyke performing artist, Lyonne said: "I didn't have the best folks. I don't think they are awful individuals. Regardless of the possibility that they were prepared to have youngsters, it is somewhat a wacky thought to put your kid in business at six years old."


Lyonne at a screening of The Immaculate Conception of Little Dizzle

When she was 16, Woody Allen cast her in Everyone Says I Love You, which prompted appearances in very nearly 30 movies throughout the following 10 years, incorporating featuring parts in the free movies Slums of Beverly Hills and But I'm a Cheerleader. Lyonne's different movies incorporate Detroit Rock City, Scary Movie 2, The Gray Zone, Kate and Leopold, Party Monster, and Blade: Trinity. She has likewise shown up on shows, for example, NBC's Will and Grace. In what is maybe her most surely understood part, she showed up as Jessica in the American Pie film arrangement.

Lyonne made movies The Immaculate Conception of Little Dizzle and Goyband. From that point forward, Lyonne has worked consistently in the New York theater scene, and in addition in film and TV. Her more up to date film appearances incorporate All About Evil, 4:44 - Last Day on Earth, Girl Most Likely, The Rambler, and Clutter.


Lyonne made her New York stage make a big appearance in the grant winning New Group generation of Mike Leigh's Two Thousand Years.

Lyonne was in the first thrown of the grant winning Love, Loss, and What I Wore, a play composed by Nora Ephron and Delia Ephron and in light of the book by Ilene Beckerman. She got rave surveys for her execution in Kim Rosenstock's comedy,Tigers Be Still at the Roundabout Theater Company: "an intensive savor the experience of the level out most clever part, the despondency crazed Grace, so profoundly drenched in self indulgence that she has thrown away any endeavors at decorum."

In 2011, Lyonne was in Tommy Nohilly's Blood From a Stone, from the New Group.

Lyonne took an interest in New Group's advantage execution of Women Behind Bars.

On living up to expectations in the theater: "There's something about theater that squashes the self-basic voices in light of the fact that you must be in the occasion. I'm happy that I didn't do this before I was prepared, before I was fit for appearing consistently. That is not an ability situated I had before."


Lyonne at The Paley Center For Media's PaleyFest 2014 Honoring Orange Is The New Black

Lyonne has shown up on the arrangement Weeds, New Girl, and Law & Order Special Victims Unit.

In late 2012, Lyonne was accounted for to be building up a TV arrangement for Fox Television around a young lady, who, crisp out of recovery and focused on beginning another life as a calm, capable grown-up, is compelled to move in with her preservationist sibling and youthful family.

She is right now featuring as Nicky Nichols in the discriminatingly acclaimed Netflix unique arrangement Orange Is the New Black, for which she has gotten positive audits. The part is Lyonne's first network show as an arrangement regular. She got her first Primetime Emmy selection for the part in 2014.

Lyonne was thrown in Amy Poehler's NBC satire pilot Old Soul in 2014. The pilot additionally stars Ellen Burstyn and was coordinated by David Wain. Poehler was essayist and official producer.

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